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Originally Posted by fiveohwblow
Super bummer man. I truly wish we knew without a doubt the true causes and could work to eradicate. I don’t think we’re anywhere near that.
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I think we are getting close! CGRP has an integral part in the mechanism of migraine/headache - it's the reason why these new CGRP inhibitors are so effective (some triptans also work in part because they stop the release of this protein). I'm pretty curious to try them actually. It's exciting because AFAIK, these CGRP inhibitors are really the first class of medications specifically designed to treat headache/migraine rather than it being a convenient side effect of the medication.